But I still have that question, because we don't have those high-cardiovascular-risk patients represented here. Answered on Jun 24, 2014
Call your doctor for medical advice about side effects. The drug may be safer for people who take it intermittently, but in some cases arthritis patients may have to weigh the risks with the benefit Celebrex provides for pain relief, the Arthritis Foundation pointed out. Celebrex (celecoxib) can occasional cause high blood pressure, liver inflammation or reduction of kidney function. Bextra Ban a Good Step, But FDA Should Pull Celebrex Too (HRG Publication #1734) [hide all summaries] The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects.
Tell your doctor if you are pregnant or plan to become pregnant while using Celebrex.Taking Celebrex during the last 3 months of pregnancy may harm a fetus. Nissen is chair of the Department of Cardiovascular Medicine.Nissen's prior research was instrumental in uncovering the cardiovascular risks associated with COX-2 inhibitors.The new study seems to reaffirm Celebrex's safety profile. All patients in post-oral surgery pain studies received a single dose of study medication. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. See below for a comprehensive list of adverse effects.
Imo, it has little or no cardiac risk otherwise.
This is not a complete list of side effects and others may occur. Compared with naproxen, celecoxib at doses of 3 and 6 mg/kg twice daily had no observable deleterious effect on growth and development during the course of the 12-week double-blind study.
Ask a doctor or pharmacist before using other medicines for … They may contain ingredients similar to celecoxib (such as aspirin, ibuprofen, ketoprofen, or naproxen). See details : Gi problems are the most common risk. "The American Heart Association also published an editorial in its journal The clinical trial is "not a study of arthritis patients at high cardiovascular risk," wrote the editorial's author, Dr. Garrett FitzGerald, a professor at the University of Pennsylvania's Perelman School of Medicine.The trial "fails to inform clinical practice," FitzGerald concluded. On eHealthMe, you can check real-world data from 16 million patients, and personalize the results to your gender and age.
You may report side effects to FDA at 1-800-FDA-1088.Stop using celecoxib and call your doctor at once if you have:This is not a complete list of side effects and others may occur. What Are Side Effects of Celebrex? 400 mg twice daily (0.5%) compared to patients on either diclofenac 75 mg twice daily (1.3%) or ibuprofen 800 mg three times daily 1.9%.The lower incidence of events with CELEBREX was maintained with or without aspirin use [see Kaplan-Meier cumulative rates at 9 months for withdrawals due to adverse events for CELEBREX, diclofenac and ibuprofen were 24%, 29%, and 26%, respectively. In the long-term polyp prevention studies in which exposure to celecoxib was 400 to 800 mg per day for up to 3 years, epicondylitis or tendon rupture were reported in at least 0.1% of patients to less than 1% of patients.Breast fibroadenosis and breast neoplasm were reported in 0.1% to 1.9% of patients taking celecoxib (the active ingredient contained in Celebrex) 100 to 200 mg twice a day or 200 mg once a day.Hypersensitivity was reported in 0.1% to 1.9% of patients taking celecoxib (the active ingredient contained in Celebrex) 100 to 200 mg twice a day or 200 mg once a day.Increased blood urea nitrogen, increased creatinine phosphokinase, Otitis media, deafness, ear abnormality, earache, and tinnitus were reported in 0.1% to 1.9% of patients taking celecoxib 100 to 200 mg twice a day or 200 mg once a day. Other side effects include: abdominal pain, dyspepsia, gastroesophageal reflux disease, peripheral edema, vomiting, and increased liver enzymes.