10.1002/pds.1993.Gengo F, Cwudzinski D, Kinkel P, Block G, Stauffer L, Lines C: Effects of treatment with lovastatin and pravastatin on daytime cognitive performance. By using this website, you agree to our While adjusting for such risk factors is important to decrease the likelihood of confounding, these are imperfect proxies and these indicators were only able to identify a small minority of the total number of alcohol users and smokers within the cohort, being those with the most severe health consequences of their behaviour. I had a heart bypass in 2010 and have been taking statins since then. 1996, 313 (7049): 75-78. 10.2165/00002512-200825090-00005.Yang CC, Jick SS, Jick H: Lipid-lowering drugs and the risk of depression and suicidal behavior. The size of the cohort also allowed for individual statins to be investigated separately, which a number of previous studies have been unable to do due to smaller sample sizes or as a result of an experimental study design [Furthermore, the use of a national cohort reduces the possibility of selection bias and increases the generalisability of these results, as it comprises a representative and diverse group of individuals across a range of socio-economic, ethnic, language, education and regional backgrounds. Analyses were conducted unadjusted, age-adjusted, and then were adjusted for other independent variables in order to account for confounding (gender, marital status, immigration status, education, family income, region of residence, and previous hospitalization for COPD, alcohol dependence and related liver disease, and CHD).
05). Drugs Aging. The effect of statin medications as a group as well as the effect of individual statins will be examined.This study is based on anonymous data from census, pharmacy, inpatient and outpatient registers for the entire Swedish population aged 40 years and over. Need it be stated, the effects on human emotionality can be extremely varied. Furthermore, lipophilic agents but not hydrophilic agents were associated with a reduction in risk of depression.
10.1097/JCP.0000000000000051.This work was supported by grants from the Swedish Research Council (K2012-70X-15428-08-3).Center for Primary Health Care Research, Lund University, Lund, SwedenCassie Redlich, Jan Sundquist, Kristina Sundquist & Xinjun LiIMPACT Strategic Research Centre, School of Medicine, Deakin University, Locked Bag 20000, Geelong, 3220, AustraliaDepartment of Psychiatry, The University of Melbourne, Parkville, AustraliaStanford Prevention Research Center, Stanford University School of Medicine, Stanford, California, USAYou can also search for this author in They are invaluable with advice and are easier to see than your GP!I've been taking a statin for 2 years and am in so much pain. These are only a few of the possible drug interactions, which is why it is very important that you discuss your medical history and all medications—prescription or otherwise—with your healthcare team before taking a statin. 2011, 35 (3): 659-663. I had a heart bypass in 2010 and have been taking statins since then. We found no beneficial effect of simvastatin as add-on therapy to interferon beta-1a. 2000, 160 (20): 3144-3152. © This article is copyrighted and may not be reproduced in any form without written permission from spacedoc.comStatements on this site are those of the credited author of the article or message and the expressed opinions are not necessarily those of the site owners, operators, developers, or hosts.Articles and messages on this site are for information and education purposes only and should not be used to diagnose or treat any illness, disease, or other medical condition.
Is it okay to take these together?
As the outcome of interest was a binary categorical variable, logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (95% CI) to represent the strength of association between use of a statin medication (any statin and by individual statins, vs. no prescription of statin medication) and subsequent diagnosis of depression during the study period.
Br J Psychiatry. The FDA warns on statin labels that some people have developed memory loss or confusion while taking statins. J Clin Psychopharmacol.
Definitive proof will come from clinical trials of statins that are able to show that the benefit of statins on mood are mediated by changes in inflammatory biomarkers.Our findings support the hypothesis that treatment with statin medications reduces the risk of subsequent development of depression. 2012, 6 (1): 42-49. These include: Atromid-S (clofibrate) Lopid (gemfibrozil) Antidepressants.
10.1001/archinte.163.16.1926.Otte C, Zhao S, Whooley MA: Statin use and risk of depression in patients with coronary heart disease: longitudinal data from the Heart and Soul Study.
This is completely out of character. Also, I've heard that statins can cause muscle problems. Neurological side effects. 2014, 28 (3): 249-272.
2011, 6 (6): 567-568. We're all used to following doctors' orders but these …
10.1016/S0306-4530(02)00014-8.Morales K, Wittink M, Datto C, DiFilippo S, Cary M, TenHave T, Katz IR: Simvastatin causes changes in affective processes in elderly volunteers. These results may go some way to explaining why previous studies have failed to conclusively confirm or refute the hypothesis that statin use may have an effect on mood and depressive symptoms, as the vast majority have either examined the effects of only one or two individual statins, or conversely have included many statins but only analysed the combined effect of the group. 2011, 230 (1): 27-34.
In fact, more than 170,000 people who take statins have been studied in detail and for extended periods of time.