Lupus can also cause the scalp hair along your hairline to become fragile and break off easily, leaving you with a ragged appearance known as lupus hair. Lupus symptoms include arthritis-like joint problems, fatigue, unexplained fever, and rashes on the face and other parts of the body. Therefore, it is important that you wash your hands regularly, maintain good personal hygiene, and notify your doctor at the first sign of any infection or fever. However, it is seldom used today because it is trickier to administer and it must be given intravenously in the hospital. In this condition, your immune system attacks various parts of your body. The upside is that hair loss from methotrexate is often temporary and reverses itself once you reduce your dosage or stop taking the medication.Remember, hair loss related to the drug isn’t usually severe. Since the side effects of steroids generally increase with the dosage, this medication generally promotes a reduction in steroid side effects as well.People with lupus have overactive immune systems. PML is an extremely rare but fatal disease, but it is important to understand that Cellcept and rituximab are not unique in their linkage to PML. DMARDs not only reduce this pain and swelling, but they may also be able to decrease long term damage to your joints.Methotrexate is one of the most commonly used drugs for the treatment of rheumatoid arthritis, and it is used in lupus patients to alleviate the joint pain and swelling of polyarthritis (arthritis involving multiple joints). Side effects include nausea and vomiting, which can sometimes be prevented with an anti-nausea medication such as ondansetron (Zofran). These medications include: cholestercholestyramine (Questran), acyclovir (Zovirax), gancyclovir (Cytovene), azathioprine (Imuran), antacids containing magnesium or aluminum hydroxide (such as Maalox, Rolaids, or Mylanta), oral contraceptives, trimethoprim/sulfamethoxazole (Bactrim),* theophylline (Theo-Dur), phenytoin (Dilantin), probenecid (Benemid), or aspirin and other salicylates.Be sure to notify your doctor immediately if you experience easy bruising or bleeding, persistent or bloody diarrhea, trouble breathing, fever, or any sign of infection.Recently, the FDA issued an alert regarding a possible relationship between Cellcept and a serious neurological disease called multifocal leukoencephalopathy (PML). In addition, about 1 in 10 patients taking leflunomide have abnormal liver function tests or decreased blood cell counts, so individuals taking this medication should have liver enzyme and blood count tests done regularly every 3-4 months. I look at the bright side, I don't have to shave or get brazilian waxed now. However, with lupus, these antibodies actually work against your own body and are produced at a rapid rate. Anyone who is on the medication and would like to have children should speak to their doctor about a medication called cholestyramine (Questran), which can help eliminate leflunomide from your body.As with other drugs that suppress your immune system, speak with your doctor about any vaccinations or surgeries you plan to have and any other medications you may be taking, including prescription drugs, over-the-counter medications, vitamins, and supplements. Your doctor will work with you to determine which treatments will work best to treat your lupus symptoms with the fewest side effects.Leflunomide is another DMARD used to treat the swelling, pain, and stiffness that many lupus patients feel due to arthritis. The risk of opportunistic infections is high.Other drugs can interfere with the absorption of the medication and increases the risk of hepatoxicity. If you take this drug for cancer or an inflammatory condition, here’s what you need to know about its possible effects on your hair.But although hair loss is a possibility with methotrexate, it isn’t a widespread side effect. Lupus can also cause the scalp hair along your hairline to become fragile and break off easily, leaving you with a ragged appearance known as lupus hair. In addition, tell your doctor if you plan to have any vaccines or surgeries, since both can pose risks for people taking immunosuppressive medications.Cyclosporine can cause serious complications during pregnancy such premature labor and high blood pressure and fluid retention in your baby, so you should not take cyclosporine if you are pregnant or may become pregnant. You should discuss this with your doctor before beginning this medication. However, a higher dose could result in more hair loss.Methotrexate can be taken as a regular prescription to treat certain conditions. Less common side effects include tremors (unintentional muscle movements), increased hair growth, muscle cramps, and numbness or tingling in your hands and feet (a condition known as neuropathy). I did not loose enough to tell it. Not sure if it is the meds or lupus but, I have no body hair at all from neck to toes. Since many lupus patients already experience sun sensitivity, try to limit sun exposure and be sure to wear sunscreen when going outdoors.It is important to remember that sometimes the side effects of this medication can go unnoticed; sometimes people may have abnormal blood tests while feeling no side effects at all, so it is important to have blood tests (complete blood counts, or “CBCs”) performed every 2-3 months while taking methotrexate.If you are pregnant, may become pregnant, or are breastfeeding, you should not take this medication because it can cause serious birth defects and complications during pregnancy. There are also instances when you might receive a single dose of the drug, such as in the case of an In single-dose uses like this, hair loss and other side effects are uncommon, but can occur. It can either be prescribed alone or in combination with other treatments, such as methotrexate; often leflunomide is prescribed for patients who do not respond well to methotrexate. In addition, try to stay out of the sun and make sure to wear sunscreen when you do go outside.Do not eat grapefruit or drink grapefruit juice while taking cyclosporine. This side effect is common, so you should drink plenty of fluids—at least 8 glasses of water—per day.