For relief of primary dysmenorrhea in adults, 500 mg initially followed by 250 mg every 6 hours as necessary. Copyright © 2018 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. If Mefenamic Acid is used in patients with severe heart failure, monitor patients for signs of worsening heart failure.Long-term administration of NSAIDs has resulted in renal papillary necrosis and other renal injury.Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. cardiovascular thrombotic events, including chest pain, shortness of breath, There are no specific antidotes. Based on available data, it is unclear that the risk for CV thrombotic events is similar for all NSAIDs. patient's needs.For the treatment of primary dysmenorrhea, the Co-morbid conditions such as coagulation disorders or concomitant use of warfarin, other anticoagulants, antiplatelet agents (e.g., aspirin), serotonin reuptake inhibitors (SSRIs) and serotonin norepinephrine reuptake inhibitors (SNRIs)mayincrease this risk. 6; gelatin, NF; glycerol monooleate; After three menstrual cycles, patients were crossed over to the alternate treatment for an additional three cycles. human dose of 250 mg showed decreased fertility.Use of NSAIDs, including mefenamic acid, during the third Because elderly patients are more likely to have

the CV effects of several therapeutic agents used to treat these medical acid is expected to be excreted in human breast milk (seeMefenamic acid is metabolized by cytochrome P450 enzyme Mefenamic acid what are its therapeutic action? The relationship of unbound fraction to drug concentration has not been studied. (e.g., difficulty breathing, swelling of the face or throat). mefenamic acid and other treatment options before deciding to use mefenamic Mefenamic acid has been reported as being greater than 90% bound to albumin. Usual Pediatric Dose for Dysmenorrhea. Use the lowest effective dose for the shortest duration consistent with individual patient treatment goals After observing the response to initial therapy with Mefenamic Acid, the dose and frequency should be adjusted to suit an individual patient's needs.For the relief of acute pain in adults and adolescents ≥14 years of age, the recommended dose is 500 mg as an initial dose followed by 250 mg every 6 hours as needed, usually not to exceed one week.For the treatment of primary dysmenorrhea, the recommended dose is 500 mg as an initial dose followed by 250 mg every 6 hours, given orally, starting with the onset of bleeding  and associated symptoms. These are not all of the possible side effects of NSAIDs. Oral dosage Adults and Adolescents >= 14 years Initially, 500 mg PO followed by 250 mg every 6 hours as needed for no longer than 7 days. mefenamic acid and other treatment options before deciding to use mefenamic Discontinuation of NSAID therapy is usually followed by recovery to the pretreatment state.No information is available from controlled clinical studies regarding the use of Mefenamic Acid in patients with advanced renal disease. worsening heart failure. Gastrointestinal bleeding has occurred. heart failure, monitor patients for signs of worsening heart failure.Long-term administration of NSAIDs has resulted in renal Do not give NSAIDs to other people, even if they Consider withdrawal of NSAIDs, including Mefenamic Acid, in women who have difficulties conceiving or who are undergoing investigation of infertility.Safety and effectiveness in pediatric patients below the age of 14 have not been established.Elderly patients, compared to younger patients, are at greater risk for NSAID-associated serious cardiovascular, gastrointestinal, and/or renal adverse reactions. Elderly patients and patients with a prior history of peptic ulcer disease and/or GI bleeding are at greater risk for serious GI events (see TABLE 1. There are no specific antidotes. Dietary administration of mefenamic acid at a dose and/or band contains citric acid, USP; D&C yellow No. trimester of pregnancy increases the risk of premature closure of the fetal Although the absolute rate of death declined somewhat after the first Clinical studies did not include a sufficient number of patients aged 65 years or older to determine if these patients respond differently.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. to seek immediate emergency help if these occur (seeAdvise patients to stop mefenamic acid immediately if Treated dams The concurrent use of aspirin and an NSAID, such as mefenamic