Cats: May see vomiting, rashes, or fever (temperature greater than 103°F). The dose range of Simplicef (cefpodoxime proxetil) tablets is 5-10 mg/kg (2.3-4.5 mg/lb) body weight, administered orally, once a day. If your pet is on any aminoglycosides (gentamicin or If you suspect or know you dog has had an overdose, please contact your veterinarian, an emergency vet clinic, or the Pet Poison Helpline at (855) 213-6680 immediately. Gastrointestinal side effects reported include vomiting, diarrhea and decreased appetite. Approved for animal use in 2005, it is a third generation cephalosporin, meaning it has a large spectrum of action against bacteria. The medication has not been studied in pregnant, breeding or lactating females. There were no deaths or permanent disabilities thought related to drug toxicity. May see lack of appetite, vomiting, or diarrhea. Cefpodoxime is more commonly known as the brand name drug called Simplicef. Cefpodoxime has limited side effects in dogs, generally related to gastrointestinal signs.Simplicef can cause allergic reactions in pets sensitive to penicillin or other cephalosporin antibiotics. According to the Zoetis data on Simplicef, fewer than 2 percent of pets studied suffered from vomiting, and even fewer showed other signs such as diarrhea.Simplicef was studied at 10 times the maximum dose in adults and puppies, with no adverse reactions seen. Use caution when giving to pets with seizures, epilepsy, or kidney disease and if your pet has any allergic reactions to the medication, contact your veterinarian immediately.People that are allergic to cephalosporin or penicillin antibiotics should not handle Cefpodoxime Proxetil as allergic reaction may occur.Consult your veterinarian when giving other medications or supplements with Cefpodoxime Proxetil as interactions may occur. Contact your veterinarian if you think your pet has any medical problems or side effects while taking Cefpodoxime Proxetil. Substances that alter the acidity of your dog’s stomach, including antacids and some drugs, can decrease the effectiveness of cefpodoxime.Elizabeth Muirhead is a practicing veterinarian with an undergraduate degree in biological sciences. Cefpodoxime Proxetil can be given with our without food.Ensure entire course of treatment is administered so the infection does not recur or worsen.If a dose of Cefpodoxime Proxetil is missed, give it as soon as you remember. In the United States, the antibiotic is market under the brand name Vantin for human use and Simplicef for dogs. A single dose is given to treat gonorrhea. Do not give two doses at one time.Dogs may also experience drooling, rashes and excitability, while cats may also experience vomiting, rashes and a fever greater than 103 degrees Fahrenheit. Cefpodoxime is a cephalosporin (SEF a low spor in) antibiotic.

Take cefpodoxime at around the same times every day.

It works by fighting bacteria in your body. Cefpodoxime comes as a tablet and suspension (liquid) to take by mouth. Cefpodoxime Overview. After an overdose, your pet should also be re-evaluated before Lactated Ringer’s Injections are continued. Learn About The Side Effects Of Simplicef. Zoetis, a division of Pfizer, manufactures Simplicef. Cefpodoxime proxetil, better known as Simplicef® or Vantin®, is an antibiotic for dogs and cats of the cephalosporin class. Cefpodoxime Proxetil Tablets are indicated for the treatment of skin infections (wounds and abscesses) in dogs. As it is in case of all the antibiotics that you could think of, even Simplicef has its own set of side effects. Dogs may also experience drooling, rashes and excitability, while cats may also experience vomiting, rashes and a fever greater than 103 degrees Fahrenheit. Possible Side Effects Side effects are rare.

If you observe any of the above signs in your pet, contact your veterinarian. Your dog might experience diarrhea.
The most common altered effects that you could see on your pet are: Vomiting of your dog, which might turn bad and take the form of nausea. SIDE EFFECTS. It will not work for viral infections (common cold, flu).Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness. Zoetis, a division of Pfizer, manufactures Simplicef. Cefpodoxime Proxetil Dosage for Dogs Weight Dosage; All weights: Give this medication exactly as directed by your veterinarian. Cefpodoxime Proxetil is used for treatment of infections, most commonly skin infections caused by susceptible strains of Always follow the dosage instructions from your veterinarian and any special instructions they may provide you.
Cefpodoxime proxetil is an oral antibiotic for veterinary and human use. Approximately 2% of dogs taking this medication experience vomiting, 1% experience diarrhea, and 1% experience reduced appetite. Puppies were as young as 18 days old, which indicates that the normal dosage used in dogs is generally safe for puppies and adults.

The medication can be given on a full or empty stomach, but giving it with food is recommended if your pet shows gastrointestinal side effects.

It is usually taken every 12 hours for 5 to 14 days depending on the condition being treated. The usual dose of cefpodoxime proxetil in dogs is 2.3-4.5 mg/lb, given by mouth, once a day for 5 to 7 days or 2 to 3 days beyond the cessation of clinical signs, up to a maximum of 28 days.