HOW TO USE: Take this medication by mouth with or without food, usually 2 to 5 times a day as directed by your doctor. Acyclovir 400 mg and more Health Canada Drug Database. Select one or more newsletters to continue. Do not use Acyclovir Cream for a condition for which it was not prescribed. In the second trial, median age of subjects was 38 years (range 18 to 87 years), 73% were female, and 94% were Caucasian. Acyclovir is among the most widely recommended antiviral drugs. 187. Yes, you can use oral Benadryl (diphenhydramine) along with topical Benadryl. Other reported clinical experience has not identified differences in responses between the elderly and younger patients. Does Acyclovir Interact with other Medications?
Subjects were instructed to initiate treatment within 1 hour of noticing signs or symptoms and continue treatment for 4 days, with application of study medication 5 times per day. Hear the instructions of your … This viral enzyme converts acyclovir into acyclovir monophosphate, a nucleotide analogue. The use of acyclovir should be advised only when the treatment evaluated outweigh the length of maternity causing. Safety and effectiveness in pediatric patients less than 12 years of age have not been established.Clinical studies of Acyclovir Cream did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Patients should be instructed to topically apply a quantity of Acyclovir Cream sufficient to cover the affected area, including the outer margin. Links to PubMed are also available for Selected References.
Results from the studies of carcinogenesis, mutagenesis and fertility are not included in the full prescribing information for Acyclovir Cream due to the minimal exposures of acyclovir that result from dermal application.
Severe Interactions. Call your doctor for medical advice about side effects. Read the Patient Information Leaflet available from your pharmacist.Consult your doctor or pharmacist if you have any questions.
Patients should be advised that Acyclovir Cream should not be used in the eye, inside the mouth or nose, or on the genitals. Three patients on Acyclovir Cream and one patient on placebo discontinued treatment due to an adverse event.An additional study, enrolling 22 healthy adults, was conducted to evaluate the dermal tolerance of Acyclovir Cream compared with vehicle using single occluded and semi-occluded patch testing methodology. Available for Android and iOS devices.
Get a printable copy (PDF file) of the complete article (319K), or click on a page image below to browse page by page. Acyclovir cream is used to treat cold sores (fever blisters; blisters that are caused by a virus called herpes simplex) on the face or lips. Drink plenty of fluids while taking this medication unless your doctor directs you otherwise.If you … The safety profile was similar to that observed in adults.Each gram of Acyclovir Cream 5% contains 50 mg acyclovir in an aqueous cream base. These concentrations would potentially expose the nursing infant to a dose of acyclovir up to 0.3 mg/kg/day. It may harm them. Systemic exposure following topical administration is minimal.However, after oral administration of Acyclovir, acyclovir concentrations have been documented in breast milk in two women and ranged from 0.6 to 4.1 times the corresponding plasma levels. Acyclovir Cream has the potential for irritation and contact sensitization.Before using Acyclovir Cream, tell your healthcare provider about all of your medical conditions, including if you:The most common side effects of Acyclovir Cream are skin reactions at the treatment site and may include: dry or cracked lips, peeling, flaking or dryness of the skin, a burning or stinging feeling, and itching.These are not all the possible side effects of Acyclovir Cream. No significant difference was observed between subjects receiving Acyclovir Cream or placebo in the prevention of progression of cold sore lesions.An open-label, uncontrolled trial with Acyclovir Cream was conducted in 113 patients aged 12 to 17 years with recurrent herpes labialis. The safety profile was similar to that observed in adults. In both studies, the mean duration of the recurrent herpes labialis episode was approximately one-half day shorter in the subjects treated with Acyclovir Cream (n = 682) compared with subjects treated with placebo (n = 703) for approximately 4.5 days versus 5 days, respectively. In this trial, therapy was applied using the same dosing regimen as in adults and subjects were followed for adverse events. Acyclovir is made use of for people detected with tiles (herpes zoster), genital herpes and chickenpox. How to use Zovirax Cream. Do not give Acyclovir Cream to other people, even if they have the same symptoms you have. Store at or below 25°C (77°F); excursions permitted to 15° to 30°C (59° to 86°F) [see USP Controlled Room Temperature].Important information: Acyclovir Cream is for use on cold sores on the lips and around the mouth only.What should I tell my healthcare provider before using Acyclovir Cream?Tell your healthcare provider about all the medicines you take,What are the possible side effects of Acyclovir Cream?Keep Acyclovir Cream and all medicines out of reach of children.General information about the safe and effective use of Acyclovir CreamWe comply with the HONcode standard for trustworthy health information -
Because they are reported voluntarily from a population of unknown size, estimates of frequency cannot be made. Acyclovir capsules, tablets, and oral suspension may be taken with meals or on an empty stomach. Patients should be advised to apply Acyclovir Cream topically 5 times per day for 4 days. If you are using acyclovir oral suspension, use a specially marked measuring spoon or other device to measure each dose accurately. The monophosphate is further converted into diphosphate by cellular guanylate kinase and into triphosphate by a number of cellular enzymes. Patients should be instructed to avoid applying other topical products to the affected area while using Acyclovir Cream. Before you use Acyclovir Cream, tell your doctor if you are pregnant, planning to become pregnant, or are breast-feeding.Treatment should be initiated at the earliest sign or symptom of recurrence.