Trop Med Int Health. You can also search for this author in J Clin Pharm Ther. Artemisinin monotherapy remains common in Africa [There is paucity of information about the quality of anti-malarials in many sub-Saharan African (SSA) countries, such as Nigeria. 10.1093/heapol/17.4.378.The United States Pharmacopeia (2000) USP 27: The National Formulary: NF 22: United States Pharmacopeial Convention, Inc., Meeting at Washington, DC., April 12–16.Basco LK: Molecular epidemiology of malaria in Cameroon.
2008, 3: e3403-10.1371/journal.pone.0003403.Taylor RB, Shakoor O, Behrens RH, Everard M, Low AS, Wangboonskul J, Reid RG, Kolawole JA: Pharmacopoeial quality of drugs supplied by Nigerian Pharmacies. In Laos, it was found that 63% of drug sellers and 80–96% of consumers were not aware of the existence of poor quality drugs [The recommended actions for improving the quality of malaria treatment may include refresher and fresh training and capacity building for all providers but with special and priority emphasis on patent medicine dealers so as to enhance their quality of drug acquisition.
2008, 78: 552-555.Chukwuani CM, Onifade M, Sumonu K: Survey of drug use practices and antibiotic prescribing pattern at a general hospital in Nigeria. J Clin Pharm Therap. All the medium/high level providers were licensed for the work that they do, with the exception of one provider from a Primary Healthcare (PHC) centre. Several medications are available for chemoprophylaxis.
Search There should be enforced checks and regulation of drug supply management as well as stiffer penalties for people stocking substandard and counterfeit drugs.People seek treatment for malaria from public sector facilities and a range of formal and informal private sector facilities [Drug quality in public and private outlets may be problematic. These remedial actions could include improved training of public and private sector providers, strengthened regulation, and consumer education.Anambra State, Southeast Nigeria was chosen for the study. 10.1016/S0035-9203(01)90252-4.Salako LA, Brieger WR, Afolabi BM, Umeh RE, Agomo PU, Asa S, Adeneye AK, Nwankwo BO, Akinlade CO: Treatment of childhood fevers and other illnesses in three rural Nigerian communities. The state has a high malaria transmission rate all year and the annual incidence rate is 10 to 35%. HK carried out the analyses to determine the drug quality. 2003, 19: 391-401. Pharmacy shops are legal drug outlets with an in-house pharmacist, whilst patent medicine dealers are also legal drug outlets without an in-house pharmacist.The drugs were purchased from both low level and high/medium level providers. In some cases, the hospitals donated the samples.
The drugs were purchased in the following quantities: artesunate – 12 tablets, dihydroartesinin – eight tablets, SP – three tablets, quinine – 10 tablets, and CQ – 10 tablets.
The objective of the study was to determine the quality of drugs used … 2006, 75: 804-811.Newton PN, Green MD, Fernandez FM, Day NPJ, White NJ: Counterfeit anti-infective drugs.
The Food and Drug Administration hasn’t approved the antimalarials to treat Covid-19, the respiratory illness caused by the coronavirus.While chloroquine is no longer used to treat malaria in Africa, some pharmacies still stock it for patients who are resistant to other anti-malaria drugs. Dissolution of CQ was performed in 900 mls of purified water and heated to a temperature of 37°C with a rotor speed of 100 rpm for 60 minutes. The few instances of known use of ACT by medium/high level providers were in general hospitals and pharmacy shops.At the time of the interview the medium/high level providers had in stock artesunate monotherapy (29.9%), CQ tablets (61.9%), CQ injection (57.7%), antibiotics (20.6%), SP (45.4%), quinine (22.1%) and ACTs (14.4%).
Ann Trop Med Parasitol. “Chloroquine is still in a testing phase in combination with other medication and not yet verified as a preventive treatment or curative option.”Nigeria’s Centre for Disease Control warned that the World Health Organization hasn’t approved use of the drug against the virus.
Health officials warn Nigerians against self-medicating Dissolution of all antifolate antimalarial products was carried out using 1 litre of 0.01 M pH 6.8 phosphate buffer solution (sodium hydroxide and potassium dihydrogen orthophosphate, Fisher Scientific) and heated to a temperature of 37°C, with a rotor speed of 75 rpm. Also, CQ tablets (90.6%) and SP formulations (84.4%) were the most common drugs used by low-level providers to treat malaria. A search of the medical literature yielded only 43 primary published research reports concerning counterfeit drugs in the world [Over the past decade, the massive public health problem of counterfeit and substandard drugs has become more manifest, leading to serious clinical consequences to patients, such as increased morbidity, mortality, and drug resistance, which leads to spurious reporting of resistance and toxicity and loss of confidence in healthcare systems [The information generated by this study will help design policy measures to strengthen the treatment component of the malaria control strategy.