However, the dose is usually not more than 600 mg per day. Mayo Clinic is a nonprofit organization and proceeds from Web advertising help support our mission. This medicine should come with a Medication Guide. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.The presence of other medical problems may affect the use of this medicine. The risk of postherpetic neuralgia increases with age, primarily affecting people older than 60.

Thus, the number of persons required for parallel and crossover trial designs is limited, and there is less risk of a period effect in a crossover trial.In a U.K. general practice survey of 3,600 to 3,800 persons (321 cases of acute herpes zoster), the annual incidence of herpes zoster was 3.4 out of 1,000; however, the incidence varied with age. However, among persons who have had acute herpes zoster, it develops in 20 percent of those 60 to 65 years of age and in greater than 30 percent of those older than 80 years.Up to 2 percent of persons with acute herpes zoster may continue to have postherpetic pain for five years or more.Oral antiviral agents (acyclovir, famciclovir, valacyclovir, and netivudine), taken during acute herpes zoster infection, may reduce the duration of postherpetic neuralgia compared with placebo. About 10 percent of all ages have postherpetic neuralgia one month after the rash, but because there is a direct relationship to age, about 50 percent will continue to be affected at 60 years of age.The main risk factor for postherpetic neuralgia is increasing age. Read about medication, prevention, symptoms, and treatment for postherpetic neuralgia. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below.

Do not double doses.If you miss a dose of the extended-release tablet after your evening meal, take it before bedtime after a snack. Pregabalin is also used for postherpetic neuralgia (pain that occurs after shingles) and pain caused by nerve damage from diabetes or a spinal cord injury. Pregabalin reduces pain and improves sleep and mood disturbances in patients with post-herpetic neuralgia: results of a randomised, placebo … Do not crush, break, or chew it. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. Search in content Using alcohol or tobacco with certain medicines may also cause interactions to occur. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Some examples of medicines that affect the CNS are antihistamines or medicine for allergies or colds, sedatives, tranquilizers, or sleeping medicines, medicine for depression, medicine for anxiety, prescription pain medicine or narcotics, medicine for attention deficit and hyperactivity disorder, medicine for seizures or barbiturates, muscle relaxants, or anesthetics, including some dental anesthetics. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur.
This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.If you miss a dose of this medicine, take it as soon as possible. For postherpetic neuralgia: For oral dosage forms (capsules and solution): Adults—At first, 75 to 150 milligrams (mg) 2 times a day, or 50 to 100 mg 3 times a day. Blood tests may be needed to check for any unwanted effects. Mental Health As you age or if your immune system is suppressed, such as from medications or chemotherapy, the virus can reactivate, causing shingles.Postherpetic neuralgia occurs if your nerve fibers are damaged during an outbreak of shingles. Children—Use and dose must be determined by your doctor.

Honkaniemi et al., 2006 31: Double-blind, placebo-controlled, randomized trial: 47 patients—41 females, 6 males; mean age: 36 years; mean duration of headache before admission: 75 hours.

"Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.© 1998-2020 Mayo Foundation for Medical Education and Research (MFMER). Do not suddenly stop taking pregabalin without checking first with your doctor. This medicine may cause sores or other skin problems (eg, skin ulcers), which may be more likely to occur in patients with diabetes. Your risk of developing postherpetic neuralgia is lessened if you begin taking antiviral medications within 72 hours of developing the shingles rash.The shingles rash is associated with an inflammation of nerves beneath the skin.Once you've had chickenpox, the virus remains in your body for the rest of your life.
Your doctor may want you or your child to gradually reduce the amount you are taking before stopping it completely.