For a full list, refer to the information leaflet that is supplied with your medicine. Registered in England and Wales. Chloroquine and Proguanil are drugs that are combined to treat malaria. This drug is also used for treating acne, so you may be able to find it more easily than some of the others. However, it is sometimes recommended that you trial your treatment before your holiday. KK Women's and Children's HospitalThe information provided is not intended as medical advice. Most side effects from this medication usually occur before the second dose.Should not be taken by travelers with a history of epilepsy or psychiatric disorders (including depression, generalized anxiety disorders, psychosis and schizophrenia) and heart conduction abnormalities.Subscribe to our mailing list to get the updates to your inboxYou may be trying to access this site from a secured browser on the server. These side effects can include inflammation of the liver, panic attacks, mouth ulcers, and peeling skin. Rarely, it may cause changes to your blood which would show up in a blood test, so you should always tell your doctor if you are using antimalarials and need a blood test.Very rare side effects can include psychosis, seizures and panic attacks but these are so rare there are no figures for their frequency.With a drug like doxycycline, Foster says: "This is a very commonly used drug and although there are fewer upset stomach incidents, it's also common to experience photosensitivity so care must be taken to avoid sunlight. Sometimes, the tablets can provoke psychiatric reactions. If you are taking Aralen, you may have nausea and/or vomiting, stomach ache, blurred vision and headaches. A number of other rare side effects have been reported, however the risk of these occurring is not precisely known. Most cases of malaria occur where antimalarials are not used, or not used carefully.Even if you're taking antimalarials, it's very important to avoid getting bitten by mosquitoes whenever possible. Don't take this medication if you have a seizure disorder. The signs include:This is a medical emergency and you need to call an ambulance or get to A&E as soon as possible.