Polytherapy: 1.01 lbs. ), the average weight loss increased in accordance with dosage: 2.31 lbs. BACKGROUND: The number of gastric restrictive bariatric operations is increasing each year, but … volume loss) than non-responders. 2009 Jun;9(6):454-63. doi: 10.1016/j.spinee.2009.02.003. It is the combination of these variables that will account for differences in weight change among users.Because hydrochlorothiazide induces water weight loss by altering kidney function (inhibiting sodium reabsorption and increasing urinary output), the amount of preexisting water retention that a user exhibits (before treatment) will probably determine the amount of weight that is lost during treatment. 25 mg/day) and increases to a higher dose (e.g. If you incur deleterious metabolic changes from hydrochlorothiazide over a long-term, there’s a chance that you may lose water weight in the short-term, and gain some body fat in the long-term.Any substances (prescription drugs, over-the-counter medications, supplements, etc.) Hydrochlorothiazide is a diuretic medication prescribed for the treatment of hypertension and edema (fluid accumulation and retention in bodily tissues) resulting from various medical conditions and prescription medications (e.g. ); 50 mg (b.i.d. Epub 2009 Apr 8.Stephens DJ, Saunders JK, Belsley S, Trivedi A, Ewing DR, Iannace V, Capella RF, Wasielewski A, Moran S, Schmidt HJ, Ballantyne GH.Surg Obes Relat Dis. If you’re a long-term hydrochlorothiazide user – how has your weight changed over time while using the medication?Note: The author of this site is not engaged in rendering professional advice or services to the individual reader. 2011 Oct;8(5):300-11. doi: 10.1016/j.genm.2011.05.007. The study involved 906 male veterans with diastolic blood pressure readings between 95 mm Hg and 114 mm Hg.Following an initial 8-week placebo run-in phase, 683 of the participants who met entry criteria (i.e. of water weight in less than 1 week.Among persons with preexisting edema as a result of a medical condition or medication side effect – the water weight loss that results from hydrochlorothiazide use may be substantial. Antidepressants have long been associated with weight gain. Additionally, the results of this study indicate that greater doses of hydrochlorothiazide are associated with more substantial weight loss than smaller doses.Maxwell et al.

While hydrochlorothiazide-mediated water depletion may yield rapid and substantial weight loss – it is important to remember that this is not body fat loss; bodily tissues are simply storing less water than before treatment.The second way by which hydrochlorothiazide can cause weight loss is through side effects.

Some sources suggest that with diuretics like hydrochlorothiazide, some individuals can lose between 10 lbs. In an additional 58 patients who responded to hydrochlorothiazide (29%), a dosage of 100 mg per day was required to attain target diastolic blood pressure reduction.Responders to the 100 mg per day dose exhibited an average weight loss of Another 38 patients who responded to hydrochlorothiazide (19%) required a dosage of 200 mg per day to attain target diastolic blood pressure reduction. Specifically, Price et al. After the 12-week trial, average weight loss of patients ranged from Results of this study indicate that standalone hydrochlorothiazide (100 mg/day) induces significant weight loss over a 12-week span among patients with edema. Most research indicates that there’s a dose-dependent effect of hydrochlorothiazide on weight such that greater weight loss occurs at high doses (than low doses).For example, in a study by Freis et al. That said, it is unknown as to whether hydrochlorothiazide might’ve induced greater weight loss than amiloride (or vice-versa).Because hydrochlorothiazide is a diuretic, the modest weight loss observed was likely attributable to a loss of water weight (rather than fat loss). patients who attained target blood pressure reduction), average weight losses were: Among hydrochlorothiazide non-responders (i.e. Epub 2013 Apr 9.Kalarchian MA, Marcus MD, Courcoulas AP, Cheng Y, Levine MD.Obesity (Silver Spring). antidiuretics) might oppose the action of hydrochlorothiazide to prevent water weight loss.For example, if you’re using the diuretic furosemide along with hydrochlorothiazide, you may lose significantly more water weight with the combination than with standalone hydrochlorothiazide – due to the synergistic diuretic actions. (200 mg/day).Because larger doses of hydrochlorothiazide will modulate kidney function to a greater extent than smaller doses – more substantial sodium and water depletion should be expected with larger doses. 2002 Feb;12(1):113-7. doi: 10.1381/096089202321144685.Khoueir P, Black MH, Crookes PF, Kaufman HS, Katkhouda N, Wang MY.Spine J. The combination of increased appetite and elevated estrogen could lead to overconsumption of calories, fat gain, and/or muscle loss. The amount of weight loss reported in studies of hydrochlorothiazide ranges from 1.01 lbs. In the event that a hydrochlorothiazide user doesn’t have much water weight to lose (such as an underweight individual who consumes a low sodium diet) – weight loss from hydrochlorothiazide may be less significant than expected.The dosage of hydrochlorothiazide that you take may impact the amount of weight loss that you experience. Among hydrochlorothiazide responders (i.e. Clipboard, Search History, and several other advanced features are temporarily unavailable. to 163.7 lbs. Average weight loss: 1.01 lbs. (1.21 kg) greater body weight reduction. Generally speaking, the larger the dose of hydrochlorothiazide that you administer, the more significant your [water] weight loss is likely to be.The total duration over which a person uses hydrochlorothiazide might also influence the amount of weight loss that occurs. When Prozac (fluoxetine) first arrived on the scene in 1988, many doctors and patients were hopeful that it might alleviate this problem. As a monotherapy, hydrochlorothiazide induces weight loss of 2.31 lbs. Only one patient discontinued hydrochlorothiazide treatment due to a combination of frequent urination and unwanted weight loss.There are a variety of variables that may influence how much weight loss occurs on hydrochlorothiazide.