In case of high-dose treatment (in particular, of both furosemide and the other drugs), this may lead to increased serum levels and an increased risk of adverse effects due to furosemide or the concomitant medication.Impairment of renal function may develop in patients receiving concurrent treatment with furosemide and high doses of certain cephalosporinsConcomitant use of ciclosporin and furosemide is associated with increased risk of gouty arthritis. What you need to know before you take Frumil TabletsDo not take Frumil Tablets if any of the above apply to you.
There was no increased incidence of mortality among patients taking other diuretics as concomitant treatment with risperidone.

If hyperkalaemia is seen, appropriate measures to reduce serum potassium must be instituted.Furosemide is a loop diuretic which acts primarily to inhibit electrolyte reabsorption in the thick ascending Loop of Henle. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.Treatment of overdosage should be aimed at reversing dehydration and correcting electrolyte imbalance, particularly hyperkalaemia. When suggestions are available use up and down arrows to review and ENTER to select. Therefore, it is recommended that lithium levels are carefully monitored and where necessary the lithium dosage is adjusted in patients receiving this combination.Risperidone: Caution should be exercised and the risks and benefits of the combination or co-treatment with furosemide or with other potent diuretics should be considered prior to the decision to use. SD = ± 1.25. Competent advice, prompt and good service are the strengths of our successful team.

Talk to your doctor before taking this medicine if you are breast-feeding or planning to breast-feed.
Check with your doctor or pharmacist if you are not sure.The usual dose is one or two tablets first thing in the morning. Nevertheless, caution should be exercised and the risks and benefits of this combination or co-treatment with other potent diuretics should be considered prior to the decision to use.

in decompensated cirrhosis of the liver) may be aggravated by furosemide treatment.

Occasionally, thrombocytopenia may occur.

Breastfeeding must be avoided during treatment with Frumil 40 mg/5 mg.Frumil 40 mg/5 mg Tablets are generally well tolerated.

Since this may lead to irreversible damage, these drugs must only be used with Frumil 40 mg/5 mg Tablets if there are compelling medical reasons. It is not known whether Amiloride Hydrochloride is excreted in breast milk.

Skin and mucous membrane reactions may occasionally occur, e.g. Amiloride may cause raised blood digoxin levels. Search emc: Enter medicine name or company GO Advanced Search > Co-Amilofruse 5mg/40mg Tablets ... Pharmacokinetic studies have been completed on Frumil 40 mg/5 mg Tablets. Regular monitoring of serum sodium, potassium, creatinine and glucose is generally recommended during therapy; particularly close monitoring is required in patients at high risk of developing electrolyte imbalances or in case of significant additional fluid loss. Treatment during pregnancy requires monitoring of foetal growth.

Irrespective of treatment, dehydration was an overall risk factor for mortality and should therefore be avoided in elderly patients with dementia (see section 4.3 Contraindications).The possibility exists of exacerbation or activation of systemic lupus erythematosus.Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine.The dosage of concurrently administered cardiac glycosides, diuretics, anti-hypertensive agents, or other drugs with blood-pressure-lowering potential may require adjustment as a more pronounced fall in blood pressure must be anticipated if given concomitantly with Frumil 40 mg/5 mg Tablets. Your tablets are available in blister packs of 4, 7, 28, 56 and 1400 tablets or bottles containing 50, 100 or 500 tablets.