Once the disorder has been adequately treated, the medication needs to be slowly tapered off and should not be stopped abruptly. Desmopressin is used most often to treat bedwetting in children who are older than five years.

DDAVP is available in two forms: a nasal spray and tablet. DDAVP tablets can cause side effects like depression, stomach upset, electrolyte imbalance, conjunctivitis, and abdominal pain. In addition, the medication should not be used during periods of illness that might affect fluid intake or the balance of electrolytes (such as in diarrhea or vomiting). Desmopressin Acetate or DDAVP is used in diabetes insipidus as well as bedwetting in children. DDAVP has few side effects. In adults and children weighing more than 10 kg, 50 mL of diluent is recommended; in children weighing 10 kg or less, 10 mL of diluent is recommended. There are a number of other conditions in which desmopressin should be used only with caution, including coronary artery disease, Although an individual would not be expected to experience most side effects—and may indeed not have any of them—some that may commonly occur with desmopressin include:

Verywell Health uses cookies to provide you with a great user experience. The prescription medication desmopressin (sometimes called DDAVP) is a drug that mimics a naturally occurring hormone in the body and is used to treat nocturnal enuresis, or bedwetting, as well as other conditions. If Desmopressin has the potential to interact with many other drugs, so current medications should be carefully reviewed by your health care provider before you start to use it. Our free guide can help you get the rest you need. Brandon Peters, MD, is a board-certified neurologist and sleep medicine specialist. DDAVP used to be used in nasal spray medications, ... (whether a nasal spray or other form) based on DDAVP/Desmopressin generally have their dosage tapered off to a lower point as time goes on – until they are completely weaned off it and instead have a normal functioning kidney process that results in no more bedwetting. Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. In addition, individuals with kidney problems, a history of low sodium (called hyponatremia), or with von Willibrand disease type IIB should not use desmopressin. DDAVP Injection 4 mcg/mL is administered as an intravenous infusion at a dose of 0.3 mcg DDAVP/kg body weight diluted in sterile physiological saline and infused slowly over 15 to 30 minutes. DDAVP allows about half the children who use it to sleep dry that night, which makes it particularly useful for sleepovers and camps.

There are a handful of potential side effects with the use of desmopressin. These occur more rarely, but some that may occur with the use of desmopressin include: By using Verywell Health, you accept our Desmopressin should not be used to treat bedwetting in children who are younger than six years old. Ⓒ 2020 About, Inc. (Dotdash) — All rights reserved Because this medication usually brings about an immediate halt to bedwetting, it is useful in these situations. It, therefore, is able to reduce diuresis or the production of urine in the kidneys that are ultimately transported into the bladder. If you experience any difficulties with the use of desmopressin, you should be in close contact with your primary health care provider. Central Cranial Diabetes Insipidus: DDAVP Nasal Spray (desmopressin acetate nasal spray) dosage must be determined for each individual patient and adjusted according to the diurnal pattern of response. Desmopressin is a drug that mimics a naturally occurring hormone in the body called antidiuretic hormone. In this situation, the restriction of fluids must accompany the medication’s administration at bedtime. Many people using this medication do not have serious side effects. Desmopressin is used most often to treat bedwetting in children who are older than five years. With the use of any drug, including desmopressin, there is a risk of serious side effects. Desmopressin Nasal Spray For Bedwetting The following leaflet for parents and carers is about the use of desmopressin for bedwetting (which is sometimes called nocturnal enuresis). This explains its other roles beyond treating bedwetting. The nasal spray can be affected by a stuffy nose from colds or allergy.