If treatment for hypertension during pregnancy is needed, other agents are preferred (ACOG 2013). Check with your physician if you have any of the following: Conditions: psychotic disorder Tell your
Management: Per US labeling: reduce afatinib by 10mg if not tolerated. No dose adjustment is needed when using ivacaftor/lumacaftor with a moderate CYP3A4 inhibitor.Ivosidenib: CYP3A4 Inhibitors (Moderate) may increase the serum concentration of Ivosidenib. Management: If this combination cannot be avoided, monitor patients for evidence of symptomatic bradycardia, and closely monitor blood pressure and heart rate during therapy. Management: Avoid concomitant use of sonidegib and moderate CYP3A4 inhibitors when possible.
Management: No action is needed in patients with normal renal function.
Management: If concurrent use cannot be avoided, reduce talazoparib dose to 0.75 mg once daily. AtorvaSTATin: May increase the serum concentration of Verapamil. Management: This interaction has only been described with intravenous dantrolene administration.Dapoxetine: CYP3A4 Inhibitors (Moderate) may increase the serum concentration of Dapoxetine. Refer to full monograph or dabigatran labeling.Dabrafenib: May decrease the serum concentration of CYP3A4 Substrates (High risk with Inducers). IMURAN should not be used for treating rheumatoid arthritis in pregnant women. Some combinations may be specifically contraindicated. This information is generalized and not intended as specific medical advice. TiZANidine: CYP1A2 Inhibitors (Weak) may increase the serum concentration of TiZANidine.
Palbociclib: May increase the serum concentration of CYP3A4 Substrates (High risk with Inhibitors).PAZOPanib: P-glycoprotein/ABCB1 Inhibitors may increase the serum concentration of PAZOPanib.
Consult appropriate labeling.RifAXIMin: P-glycoprotein/ABCB1 Inhibitors may increase the serum concentration of RifAXIMin. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. Lithium: Calcium Channel Blockers (Nondihydropyridine) may enhance the neurotoxic effect of Lithium. Calan SR/Isoptin/Isoptin SR/Verapamil/Verapamil Hydrochloride Oral Tab ER: 120mg, 180mg, 240mg ... CONTRAINDICATIONS / PRECAUTIONS. Celiprolol: Verapamil may enhance the bradycardic effect of Celiprolol. Avoid repeated injections of IV verapamil in patients with significant renal failure.• Drug-drug interactions: Potentially significant interactions may exist, requiring dose or frequency adjustment, additional monitoring, and/or selection of alternative therapy.
Management: Concurrent use of felodipine or nisoldipine with itraconazole is specifically contraindicated. Management: The labeling for some US and Canadian calcium channel blockers contraindicate use with rifampin, however recommendations vary. See full drug interaction monograph for details.Esmolol: Calcium Channel Blockers (Nondihydropyridine) may enhance the bradycardic effect of Esmolol. Management: The bromocriptine dose should not exceed 1.6 mg daily with use of a moderate CYP3A4 inhibitor. Avoid repeated injections of IV verapamil in patients with significant hepatic failure.• Hypertrophic cardiomyopathy (HCM): Use with caution in patients with HCM with outflow tract obstruction (especially those with high gradients, advanced heart failure, or sinus bradycardia); may be used in patients who cannot tolerate beta-blockade.
Acalabrutinib: CYP3A4 Inhibitors (Moderate) may increase the serum concentration of Acalabrutinib. Consult appropriate manufacturer labeling.Stiripentol: May increase the serum concentration of CYP3A4 Substrates (High risk with Inhibitors). This is not a list of all drugs or health problems that interact with bromocriptine (parlodel). Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, Available for Android and iOS devices.We comply with the HONcode standard for trustworthy health information -
Calcium Channel Blockers (Nondihydropyridine) may increase the serum concentration of Cardiac Glycosides.
Kliegman RM, Stanton BMD, St. Geme J, Schor NF, eds. INDICATIONS Hyperprolactinemia-Associated Dysfunctions. Ethanol: Verapamil may increase blood ethanol levels and prolong its effects.
Excipient information presented when available (limited, particularly for generics); consult specific product labeling.Capsule Extended Release 24 Hour, Oral, as hydrochloride:Isoptin SR: 240 mg [contains FD&C BLUE #2 ALUMINUM LAKE, FD&C YELLOW #10 ALUMINUM LAKE] Quinagolide: May enhance the hypotensive effect of Blood Pressure Lowering Agents.QuiNIDine: May enhance the hypotensive effect of Verapamil. Tezacaftor: CYP3A4 Inhibitors (Moderate) may increase the serum concentration of Tezacaftor. Clinical practice guidelines for the management of hypertension in the community: a statement by the American Society of Hypertension and the International Society of Hypertension. If used together, limit adult maximum simvastatin dose to 10 mg/day, and avoid Simcor (simvastatin/niacin) because fixed simvastatin doses in the product exceed this maximum.Sincalide: Drugs that Affect Gallbladder Function may diminish the therapeutic effect of Sincalide. KN95 masks are effective, according to the CDC, in helping to prevent the spread of virus transmission from person to person. For some products it does not matter. Management: When treating B-cell malignancies, decrease ibrutinib to 280 mg daily when combined with moderate CYP3A4 inhibitors. See full drug interaction monograph for details.Encorafenib: CYP3A4 Inhibitors (Moderate) may increase the serum concentration of Encorafenib.