Less than 2% of the dose enters systemic circulation as benzoic acid. Author information: (1)University of Pennsylvania Health System, Philadelphia, USA. Many of these side effects can be managed, and some may go away on their own over time.All material copyright MediResource Inc. 1996 – 2020. Do not use extra medicine to make up the missed dose.Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.Overdose symptoms include bloody or watery diarrhea, which may result if you absorb benzoyl peroxide and clindamycin topical through your skin by applying too much.Avoid using skin products that can cause irritation, such as harsh soaps, shampoos, or skin cleansers, hair coloring or permanent chemicals, hair removers or waxes, or skin products with alcohol, spices, astringents, or lime.Avoid using other medications on the areas you treat with benzoyl peroxide and clindamycin topical unless your doctor tells you to.Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. It is suggested that the lipophilic nature of benzoyl peroxide acts to concentrate the compound into the lipid-rich sebaceous follicle.The pharmacokinetics (plasma and urine) of clindamycin from The amount of clindamycin excreted in the urine during the 12 hour dosing interval increased from a mean (SD) of 5745 (3130) ng on Day 1 to 12069 (7660) ng on Day 5. Do not use benzoyl peroxide and clindamycin topical in larger or smaller amounts or for longer than recommended.Using more medicine or applying it more often than prescribed will not make it work any faster, and may increase side effects.Wash your hands before and after applying this medicine.Wash your face with a mild cleanser (not soap) and pat the skin dry with a clean towel.Benzoyl peroxide and clindamycin topical is usually applied twice daily, in the morning and evening.Avoid getting this medicine in your eyes, mouth, or nose (or in the creases of your nose), or on your lips. June 28, 2019 ENDOSCOPIC EXAMINATION MAY REVEAL PSEUDOMEMBRANOUS COLITIS. This study compares the combination treatment of 1% clindamycin and 5% benzoyl peroxide topical gel with other therapeutic options for mild to moderately severe acne vulgaris. This combination product contains two medications: clindamycin and benzoyl peroxide. Do not apply this medicine to sunburned, windburned, dry, chapped, irritated, or broken skin.It may take several weeks before your symptoms improve. The aqueous gel vehicle is less drying, and there is no photosensitivity associated with its use. Keep tightly closed. Conclusion: Clindamycin/benzoyl peroxide gel had better tolerability with regard to erythema, dryness, and peeling than adapalene/benzoyl peroxide gel during the first two weeks of treatment. 16714-984-50 Manufacturer Perrigo Pharmaceuticals has issued a voluntary recall for clindamycin/benzoyl peroxide gel (1.2%/5%), a topical medication used to treat

2001;2(1):33-9. doi: 10.2165/00128071-200102010-00006.Ellis CN, Leyden J, Katz HI, Goldfarb MT, Hickman J, Jones TM, Tschen E.Tschen EH, Katz HI, Jones TM, Monroe EW, Kraus SJ, Connolly MA, Levy SF.Am J Clin Dermatol. When used in tandem, they promise greater efficacy than either individual agent through their antibacterial and anti-inflammatory effects. You may report side effects to FDA at 1-800-FDA-1088.Benzoyl peroxide 2.5 %-clindamycin 1.2%: Apply a pea-sized amount topically to the face once a dayIt is not likely that other drugs you take orally or inject will have an effect on topically applied benzoyl peroxide and clindamycin. 2003;42(14):1287-304. doi: 10.2165/00003088-200342140-00005. We comply with the HONcode standard for trustworthy health information - Patients who develop allergic symptoms such as severe swelling or shortness of breath should discontinue Benzoyl peroxide has been shown to be a tumor promoter and progression agent in a number of animal studies. Do not freeze. Leyden JJ(1), Hickman JG, Jarratt MT, Stewart DM, Levy SF.
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Clindamycin belongs to the family of medications known as Each 1 g of gel contains 10 mg of clindamycin and 50 mg of benzoyl peroxide. Patients were evaluated and acne lesions counted at each clinical visit; weeks 2, 4, 6, 8 and 10.

The Table below lists local adverse events reported by at least 1% of patients in the clindamycin and benzoyl peroxide gel and vehicle groups.Local Adverse Events – all causalities in >/= 1% of patientsAnaphylaxis, as well as allergic reactions leading to hospitalization, have been reported during post-marketing use of clindamycin/benzoyl peroxide products. Keep using the medication as directed and tell your doctor if your symptoms do not improve.Once in use, store the gel at room temperature away from moisture and heat. If needed, add additional purified water to bring level up to the mark. Epub 2019 Jun 1.Ther Clin Risk Manag. This site needs JavaScript to work properly. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.Avoid using sunscreen containing PABA on the same skin treated with benzoyl peroxide and clindamycin topical, or skin discoloration may occur.Benzoyl peroxide can bleach hair or fabrics.

If a moisturizer was required, the patients were provided a moisturizer to be used as needed.

We anticipate reposting the images once we are able identify and filter out images that do not match the information provided in the drug labels.

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