Malignancy Patients receiving immunosuppressants, including Azathioprine, are at increased risk of developing lymphoma and other malignancies, particularly of the skin. Azathioprine is immunosuppressive, delayed hypersensitivity and cellular cytotoxicity tests being suppressed to a greater degree than are antibody responses.
You should not need a new prescription for this medication to be refilled. All rights reserved. If this drug is used during pregnancy or if the patient becomes pregnant while taking this drug, the patient should be apprised of the potential hazard to the fetus. It is suggested that patients on Azathioprine have complete blood counts, including platelet counts, weekly during the first month, twice monthly for the second and third months of treatment, then monthly or more frequently if dosage alterations or other therapy changes are necessary. In a detailed case report, Benefit versus risk must be weighed carefully before use of Azathioprine tablets in patients of reproductive potential. It comes with serious risks if you don’t take it as prescribed.If you’re taking it for rheumatoid arthritis, your symptoms may not improve or they may get worse over time.If you’re taking this drug for rheumatoid arthritis and you stop taking it suddenly, your symptoms of rheumatoid arthritis may come back again.Never try to catch up by taking two doses at once. Azathioprine is in a class of medications called immunosuppressants. These effects usually happen within the first few weeks of starting the medication. Severe C. diff associated... allergic re…Food: none except delay peak ... Chelate with cations: Al, Mg, C…N/V/D, abdominal pain, dyspepsia... CNS: dizzy, insomnia, or som…Amphoteracin B... Aminoglycosides... Sulfamethoxazole/trimethoprimAmphoteracin B, Aminoglycosides, Sulfamethoxazole/trimethorprimaasai increase: ACEI/ARB, antibiotics, thiazide, NSAIDS except…alteration of intestinal flora: metronidazole, quinolones; CYP…CYP2C9 induction: Rifampin, phenytoin, SJW; increase coagulati…aasai increase: ACEI/ARB, antibiotics, thiazide, NSAIDS except…penicillins and other beta lactam antibiotics, sulfonamidescardiac glycosides, sildenafil and other 'nafils, quinidineACE inhibitors, metronizadole, carbonic anhydrase inhibitorspenicillins and other beta lactam antibiotics, sulfonamidesLinezolid is an antibiotic with monoamine oxidase inhibitor-ty…Clients who are prescribed oral estrogen contraceptives (with…Metronidazole (Flagyl) is used to treat trichomoniasis and ame…Many antihistamines also have anticholinergic effects. These infections may lead to serious, including fatal outcomes.Cases of JC virus-associated infection resulting in progressive multifocal leukoencephalopathy (PML), sometimes fatal, have been reported in patients treated with immunosuppressants, including Azathioprine.
Both compounds are rapidly eliminated from blood and are oxidized or methylated in erythrocytes and liver; no Azathioprine or mercaptopurine is detectable in urine after 8 hours.
Azathioprine is a prescription medication. Let us know if you have any questions regarding this information. These effects should happen after about 12 weeks of being on the medication.Keep these considerations in mind if your doctor prescribes azathioprine for you.A prescription for this medication is refillable. Therefore, immunosuppressive drug therapy should be maintained at the lowest effective levels.Information is available on the risk of malignancy with the use of Azathioprine in rheumatoid arthritis (see Postmarketing cases of hepatosplenic T-cell lymphoma (HSTCL), a rare type of T-cell lymphoma, have been reported in patients treated with Azathioprine.